ATG4D protein (Delphinapterus leucas) - STRING interaction network

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Score

ATG4D

Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (473 aa)

Predicted Functional Partners:

GABARAPL1

0.975

GABARAP

0.975

GABARAPL2

0.974

ATG3

0.785

MAP1LC3B

0.777

MAP1LC3A

0.741

MAP1LC3C

0.696

ATG7

0.687

ATG12

0.654

ATG5

0.651

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG12	ATG3	A0A2Y9PU20	A0A2Y9QEJ2	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy-related protein 3.	0.999
ATG12	ATG4D	A0A2Y9PU20	A0A2Y9LT96	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.654
ATG12	ATG5	A0A2Y9PU20	A0A2Y9LPY0	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
ATG12	ATG7	A0A2Y9PU20	A0A2Y9MHI4	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.999
ATG12	GABARAP	A0A2Y9PU20	A0A2Y9Q6V4	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Gamma-aminobutyric acid receptor-associated protein.	0.980
ATG12	GABARAPL1	A0A2Y9PU20	A0A2Y9NGT6	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Gamma-aminobutyric acid receptor-associated protein-like 1.	0.980
ATG12	GABARAPL2	A0A2Y9PU20	A0A2Y9P697	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Gamma-aminobutyric acid receptor-associated protein-like 2 isoform X1.	0.980
ATG12	MAP1LC3A	A0A2Y9PU20	A0A2Y9PRY2	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Microtubule-associated proteins 1A/1B light chain 3A.	0.826
ATG12	MAP1LC3B	A0A2Y9PU20	A0A2Y9P080	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Microtubule-associated proteins 1A/1B light chain 3B.	0.860
ATG12	MAP1LC3C	A0A2Y9PU20	A0A2Y9NYR2	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Microtubule-associated proteins 1A/1B light chain 3C.	0.759
ATG3	ATG12	A0A2Y9QEJ2	A0A2Y9PU20	Autophagy-related protein 3.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.999
ATG3	ATG4D	A0A2Y9QEJ2	A0A2Y9LT96	Autophagy-related protein 3.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.785
ATG3	ATG5	A0A2Y9QEJ2	A0A2Y9LPY0	Autophagy-related protein 3.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.998
ATG3	ATG7	A0A2Y9QEJ2	A0A2Y9MHI4	Autophagy-related protein 3.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.999
ATG3	GABARAP	A0A2Y9QEJ2	A0A2Y9Q6V4	Autophagy-related protein 3.	Gamma-aminobutyric acid receptor-associated protein.	0.993
ATG3	GABARAPL1	A0A2Y9QEJ2	A0A2Y9NGT6	Autophagy-related protein 3.	Gamma-aminobutyric acid receptor-associated protein-like 1.	0.993
ATG3	GABARAPL2	A0A2Y9QEJ2	A0A2Y9P697	Autophagy-related protein 3.	Gamma-aminobutyric acid receptor-associated protein-like 2 isoform X1.	0.992
ATG3	MAP1LC3A	A0A2Y9QEJ2	A0A2Y9PRY2	Autophagy-related protein 3.	Microtubule-associated proteins 1A/1B light chain 3A.	0.877
ATG3	MAP1LC3B	A0A2Y9QEJ2	A0A2Y9P080	Autophagy-related protein 3.	Microtubule-associated proteins 1A/1B light chain 3B.	0.892
ATG3	MAP1LC3C	A0A2Y9QEJ2	A0A2Y9NYR2	Autophagy-related protein 3.	Microtubule-associated proteins 1A/1B light chain 3C.	0.853