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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CEBPDCCAAT/enhancer-binding protein. (256 aa)    
Predicted Functional Partners:
KLF5
Krueppel-like factor 5.
    
 0.744
DDIT4
DNA damage-inducible transcript 4 protein.
   
  
 0.702
CEBPB
CCAAT/enhancer-binding protein.
   
0.683
CREB1
Cyclic AMP-responsive element-binding protein 1 isoform X1.
   
 0.654
SMAD4
Mothers against decapentaplegic homolog.
    
 
 0.643
DKK1
Dickkopf-related protein 1.
      
 0.619
LOC111177826
Cytochrome c oxidase subunit 5A, mitochondrial isoform X1.
   
 0.615
CO2
Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.
    
 0.580
ATF4
Cyclic AMP-dependent transcription factor ATF-4 isoform X1.
   
 0.567
LOC111162930
Cytochrome c oxidase subunit 7C, mitochondrial.
   
 0.558
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.