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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SORCS2VPS10 domain-containing receptor SorCS2 isoform X1. (1171 aa)    
Predicted Functional Partners:
NGF
Beta-nerve growth factor; Belongs to the NGF-beta family.
    
 
 0.902
GAK
cyclin-G-associated kinase isoform X1.
   
 
 0.779
SH3TC1
SH3 domain and tetratricopeptide repeat-containing protein 1 isoform X1.
      
 0.731
SORT1
Sortilin.
    
 
0.730
ABLIM2
Actin-binding LIM protein 2 isoform X1.
      
 0.664
ST6GALNAC3
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 isoform X1; Belongs to the glycosyltransferase 29 family.
      
 0.663
NTS
Neurotensin/neuromedin N isoform X1.
    
 
 0.627
HIVEP2
Transcription factor HIVEP2.
    
 
 0.623
CMIP
C-Maf-inducing protein isoform X1.
      
 0.599
BDNF
Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.
    
 
 0.582
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.