| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADSS | ADSSL1 | A0A2Y9NM91 | A0A2Y9NQM8 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.901 |
| ADSS | DOHH | A0A2Y9NM91 | A0A2Y9LUY0 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. | 0.815 |
| ADSS | LOC111169417 | A0A2Y9NM91 | A0A2Y9MEB9 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Multifunctional protein ADE2 isoform X2. | 0.729 |
| ADSSL1 | ADSS | A0A2Y9NQM8 | A0A2Y9NM91 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.901 |
| ADSSL1 | DOHH | A0A2Y9NQM8 | A0A2Y9LUY0 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. | 0.815 |
| ADSSL1 | LOC111169417 | A0A2Y9NQM8 | A0A2Y9MEB9 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Multifunctional protein ADE2 isoform X2. | 0.729 |
| DHPS | DOHH | A0A2Y9LWN2 | A0A2Y9LUY0 | Deoxyhypusine synthase. | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. | 0.962 |
| DHPS | EIF5A | A0A2Y9LWN2 | A0A2Y9Q7K6 | Deoxyhypusine synthase. | Eukaryotic translation initiation factor 5A. | 0.961 |
| DHPS | EIF5A2 | A0A2Y9LWN2 | A0A2Y9NFP6 | Deoxyhypusine synthase. | Eukaryotic translation initiation factor 5A. | 0.978 |
| DHPS | LOC111163382 | A0A2Y9LWN2 | A0A2Y9LDQ2 | Deoxyhypusine synthase. | Eukaryotic translation initiation factor 5A. | 0.961 |
| DHPS | SMS | A0A2Y9LWN2 | A0A2Y9M392 | Deoxyhypusine synthase. | Spermine synthase. | 0.782 |
| DOHH | ADSS | A0A2Y9LUY0 | A0A2Y9NM91 | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.815 |
| DOHH | ADSSL1 | A0A2Y9LUY0 | A0A2Y9NQM8 | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.815 |
| DOHH | DHPS | A0A2Y9LUY0 | A0A2Y9LWN2 | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. | Deoxyhypusine synthase. | 0.962 |
| DOHH | EIF5A | A0A2Y9LUY0 | A0A2Y9Q7K6 | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. | Eukaryotic translation initiation factor 5A. | 0.928 |
| DOHH | EIF5A2 | A0A2Y9LUY0 | A0A2Y9NFP6 | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. | Eukaryotic translation initiation factor 5A. | 0.962 |
| DOHH | FH | A0A2Y9LUY0 | A0A2Y9NJE6 | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. | Fumarate hydratase, mitochondrial. | 0.827 |
| DOHH | GPD2 | A0A2Y9LUY0 | A0A2Y9MX04 | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. | Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.831 |
| DOHH | LOC111163382 | A0A2Y9LUY0 | A0A2Y9LDQ2 | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. | Eukaryotic translation initiation factor 5A. | 0.928 |
| DOHH | LOC111169417 | A0A2Y9LUY0 | A0A2Y9MEB9 | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. | Multifunctional protein ADE2 isoform X2. | 0.821 |
STRING v12.5 is now available!
