| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CASR | GNA11 | A0A2Y9MP07 | A0A2Y9LWA4 | Extracellular calcium-sensing receptor isoform X1. | Guanine nucleotide-binding protein subunit alpha-11. | 0.959 |
| CASR | GRK2 | A0A2Y9MP07 | A0A2Y9PJ88 | Extracellular calcium-sensing receptor isoform X1. | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. | 0.619 |
| CASR | PLCB1 | A0A2Y9MP07 | A0A2Y9LS93 | Extracellular calcium-sensing receptor isoform X1. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. | 0.950 |
| CASR | PLCB2 | A0A2Y9MP07 | A0A2Y9PAZ4 | Extracellular calcium-sensing receptor isoform X1. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. | 0.956 |
| CASR | PLCB3 | A0A2Y9MP07 | A0A2Y9PNQ6 | Extracellular calcium-sensing receptor isoform X1. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. | 0.948 |
| CASR | PLCB4 | A0A2Y9MP07 | A0A2Y9LTY4 | Extracellular calcium-sensing receptor isoform X1. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. | 0.919 |
| CCKAR | GNA11 | A0A2Y9MKV2 | A0A2Y9LWA4 | Cholecystokinin receptor type A; Belongs to the G-protein coupled receptor 1 family. | Guanine nucleotide-binding protein subunit alpha-11. | 0.963 |
| CCKAR | GRK2 | A0A2Y9MKV2 | A0A2Y9PJ88 | Cholecystokinin receptor type A; Belongs to the G-protein coupled receptor 1 family. | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. | 0.552 |
| CCKAR | PLCB1 | A0A2Y9MKV2 | A0A2Y9LS93 | Cholecystokinin receptor type A; Belongs to the G-protein coupled receptor 1 family. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. | 0.514 |
| CCKAR | PLCB2 | A0A2Y9MKV2 | A0A2Y9PAZ4 | Cholecystokinin receptor type A; Belongs to the G-protein coupled receptor 1 family. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. | 0.514 |
| CCKAR | PLCB3 | A0A2Y9MKV2 | A0A2Y9PNQ6 | Cholecystokinin receptor type A; Belongs to the G-protein coupled receptor 1 family. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. | 0.407 |
| CHRM1 | CHRM5 | A0A2Y9PVR9 | A0A2Y9PHR5 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | 0.921 |
| CHRM1 | GNA11 | A0A2Y9PVR9 | A0A2Y9LWA4 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | Guanine nucleotide-binding protein subunit alpha-11. | 0.961 |
| CHRM1 | GRK2 | A0A2Y9PVR9 | A0A2Y9PJ88 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. | 0.449 |
| CHRM1 | PLCB1 | A0A2Y9PVR9 | A0A2Y9LS93 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. | 0.429 |
| CHRM1 | PLCB2 | A0A2Y9PVR9 | A0A2Y9PAZ4 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. | 0.421 |
| CHRM5 | CHRM1 | A0A2Y9PHR5 | A0A2Y9PVR9 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | 0.921 |
| CHRM5 | GNA11 | A0A2Y9PHR5 | A0A2Y9LWA4 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | Guanine nucleotide-binding protein subunit alpha-11. | 0.965 |
| CHRM5 | GRK2 | A0A2Y9PHR5 | A0A2Y9PJ88 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. | 0.578 |
| CHRM5 | PLCB1 | A0A2Y9PHR5 | A0A2Y9LS93 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. | 0.544 |