Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
JUPJunction plakoglobin. (744 aa)    
Predicted Functional Partners:
CDH1
Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins.
   
 0.996
CTNNB1
Catenin beta-1.
   
 0.995
DSP
Desmoplakin isoform X1.
   
 0.992
DSG1
Desmoglein-1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
   
 0.991
PKP2
Plakophilin-2 isoform X1.
   
 0.990
DSG2
Desmoglein-2.
   
 0.988
DSG3
LOW QUALITY PROTEIN: desmoglein-3.
   
 0.988
PKP1
Plakophilin-1 isoform X2.
   
 0.983
APC
Adenomatous polyposis coli protein isoform X1.
   
 0.975
TCF7L1
Transcription factor 7-like 1 isoform X1.
    
 0.971
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.