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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JUPJunction plakoglobin. (744 aa)    
Predicted Functional Partners:
CDH1
Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins.
   
 0.984
TCF7L1
Transcription factor 7-like 1 isoform X1.
    
 0.973
LEF1
Lymphoid enhancer-binding factor 1 isoform X1.
    
 0.973
TCF7L2
Transcription factor 7-like 2 isoform X1.
    
 0.973
TCF7
Transcription factor 7 isoform X1.
    
 0.973
CTNNB1
Catenin beta-1.
  
 
0.960
DSP
Desmoplakin isoform X1.
   
 0.928
APC
Adenomatous polyposis coli protein isoform X1.
   
 0.911
CCDC130
Coiled-coil domain-containing protein 130 isoform X1.
   
   0.904
PKP1
Plakophilin-1 isoform X2.
   
 0.890
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.