close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SESN1Sestrin-1 isoform X1. (551 aa)    
Predicted Functional Partners:
SESN2
Sestrin-2.
  
  
0.951
SESN3
Sestrin-3 isoform X1.
  
  
0.931
WDR24
GATOR complex protein WDR24 isoform X1.
    
 0.875
PRKAB1
5'-AMP-activated protein kinase subunit beta-1.
     
 0.859
PRKAA2
Non-specific serine/threonine protein kinase.
     
 0.851
PRKAG2
5'-AMP-activated protein kinase subunit gamma-2 isoform X1.
   
 
 0.831
PRKAG1
5'-AMP-activated protein kinase subunit gamma-1 isoform X1.
   
 
 0.829
PRKAG3
5'-AMP-activated protein kinase subunit gamma-3.
   
 
 0.827
MIOS
GATOR complex protein MIOS.
    
 0.809
DEPDC5
GATOR complex protein DEPDC5 isoform X1.
    
 0.792
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.