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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM161ATransmembrane protein 161A. (479 aa)    
Predicted Functional Partners:
POPDC2
Popeye domain-containing protein 2 isoform X1.
      
 0.786
KLHL31
Kelch-like protein 31.
      
 0.766
TMEM38A
Trimeric intracellular cation channel type A.
      
 0.735
TMEM214
Transmembrane protein 214 isoform X1.
      
 0.649
TMX4
Thioredoxin-related transmembrane protein 4.
      
 0.644
RHBDD1
Rhomboid-related protein 4 isoform X1.
      
 0.637
TMEM70
Transmembrane protein 70, mitochondrial isoform X1.
      
 0.582
SPPL2A
Signal peptide peptidase-like 2A.
   
  
 0.522
RSAD1
Radical S-adenosyl methionine domain-containing protein; May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen- III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L- methionine; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
      
 0.516
TMEM174
Transmembrane protein 174.
      
 0.510
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.