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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCMF1E3 ubiquitin-protein ligase KCMF1 isoform X1. (456 aa)    
Predicted Functional Partners:
UBR4
E3 ubiquitin-protein ligase UBR4 isoform X1.
    
 
 0.908
CUL3
Cullin-3 isoform X1; Belongs to the cullin family.
   
  
 0.553
PPM1A
Protein phosphatase 1A.
   
    0.535
ZNF574
Zinc finger protein 574.
    
 
 0.518
PTPRS
Receptor-type tyrosine-protein phosphatase S isoform X1.
      
 0.517
ISCU
Iron-sulfur cluster assembly enzyme ISCU, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.
      
 0.515
MANBAL
Protein MANBAL.
      
 0.514
SLC17A3
Sodium-dependent phosphate transport protein 4.
      
 0.506
NDE1
Nuclear distribution protein nudE homolog 1 isoform X1.
      
 0.505
THSD7A
Thrombospondin type-1 domain-containing protein 7A isoform X1.
      
 0.497
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.