close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
POLNDNA polymerase nu. (901 aa)    
Predicted Functional Partners:
HELQ
Helicase POLQ-like isoform X1.
 
  
 
 0.886
FANCM
Fanconi anemia group M protein isoform X1.
   
 
 0.724
FANCD2
Fanconi anemia group D2 protein isoform X1.
   
 0.712
POLG
DNA polymerase subunit gamma-1 isoform X1.
   
  
 0.706
FANCI
Fanconi anemia group I protein isoform X2.
   
 0.639
DNAJA3
dnaJ homolog subfamily A member 3, mitochondrial isoform X1.
    
 
 0.614
SART3
Squamous cell carcinoma antigen recognized by T-cells 3 isoform X1.
      
 0.612
HAUS3
HAUS augmin-like complex subunit 3.
 
 
  
 0.600
FANCA
Fanconi anemia group A protein isoform X1.
   
 0.596
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 
 0.596
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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