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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COL10A1Collagen alpha-1(X) chain. (705 aa)    
Predicted Functional Partners:
LOC111167571
Collagenase 3.
   
 0.730
RUNX2
Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
     
 0.709
LOC111182889
LOW QUALITY PROTEIN: transcription factor SOX-9-like.
   
 
 0.703
IHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
      
 0.630
ALPL
Alkaline phosphatase.
      
 0.607
COMP
Cartilage oligomeric matrix protein.
   
 0.600
P3H2
Prolyl 3-hydroxylase 2 isoform X1.
    
 0.597
PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor isoform X1; Belongs to the G-protein coupled receptor 2 family.
    
 0.574
SERPINH1
Serpin H1; Belongs to the serpin family.
   
 0.569
PLOD3
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3.
   
 0.564
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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