Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
COL10A1Collagen alpha-1(X) chain. (705 aa)    
Predicted Functional Partners:
LOC111167571
Collagenase 3.
   
 0.808
RUNX2
Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
    
 0.780
LOC111182889
LOW QUALITY PROTEIN: transcription factor SOX-9-like.
   
 
 0.605
PTHLH
Parathyroid hormone-related protein.
     
 0.594
SP7
Transcription factor Sp7.
    
 0.573
COL2A1
Collagen alpha-1(II) chain.
   
 0.560
COL8A2
Collagen alpha-2(VIII) chain.
   
 
  0.557
COL4A2
Collagen alpha-2(IV) chain isoform X1.
  
 
 
0.554
IHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
      
 0.538
COMP
Cartilage oligomeric matrix protein.
   
 0.532
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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