close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TACC3Transforming acidic coiled-coil-containing protein 3 isoform X1. (822 aa)    
Predicted Functional Partners:
AURKA
Aurora kinase A isoform X2; Belongs to the protein kinase superfamily.
   
 0.917
PLK1
Serine/threonine-protein kinase PLK.
   
 0.893
BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta.
   
 
 0.881
CDCA8
Borealin isoform X2.
   
  
 0.846
KIF22
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.828
CKAP5
Cytoskeleton-associated protein 5 isoform X3.
    
 
 0.804
TPX2
Targeting protein for Xklp2 isoform X1.
   
 0.798
BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1.
   
 
 0.788
AURKB
Aurora kinase B isoform X1; Belongs to the protein kinase superfamily.
   
 0.757
CLTC
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
    
 
 0.752
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.