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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KDM3ALysine-specific demethylase 3A isoform X1. (1322 aa)    
Predicted Functional Partners:
KDM3B
Lysine-specific demethylase 3B isoform X1.
  
 
 
0.935
PRKACA
cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily.
   
 
 0.910
PRKACB
cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily.
   
 
 0.910
LOC111168952
Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]
    
  0.902
KDM4A
Lysine-specific demethylase 4A isoform X1.
     
 0.780
KDM5A
Lysine-specific demethylase 5A isoform X1.
   
 
 0.761
SMARCA4
Transcription activator BRG1 isoform X4.
   
 
 0.726
SMARCA2
Probable global transcription activator SNF2L2 isoform X1.
   
 
 0.726
ACTB
Actin, cytoplasmic 1.
     
 0.686
SMARCC1
SWI/SNF complex subunit SMARCC1 isoform X1.
   
 
 0.686
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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