Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCAMCell surface glycoprotein MUC18 isoform X1. (638 aa)    
Predicted Functional Partners:
LAMA4
Laminin subunit alpha-4 isoform X1.
   
 0.933
CNTN1
Contactin-1 isoform X1.
    
 0.848
ATP6V0A2
V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
    
  0.782
ATP6V0A1
V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
    
  0.781
ENG
Endoglin.
   
 
 0.559
THY1
Thy-1 membrane glycoprotein.
   
 
 0.546
PTPRC
Receptor-type tyrosine-protein phosphatase C isoform X1.
    
 0.530
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
   
 0.517
LAMA3
Laminin subunit alpha-3 isoform X3.
   
 0.513
LAMA5
Laminin subunit alpha-5.
   
 0.513
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.