close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORMDL3ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)    
Predicted Functional Partners:
SPTLC1
Serine palmitoyltransferase 1.
    
 0.902
SPTLC2
Serine palmitoyltransferase 2 isoform X1.
    
 0.829
SPTLC3
Serine palmitoyltransferase 3 isoform X2.
    
 
 0.744
SPTSSA
Serine palmitoyltransferase small subunit A.
    
 
 0.679
ZPBP2
Zona pellucida-binding protein 2 isoform X1.
      
 0.612
LRRC3C
Leucine-rich repeat-containing protein 3C.
      
 0.611
LOC111184396
Disintegrin and metalloproteinase domain-containing protein 33-like isoform X1.
     
 0.611
DEGS1
Sphingolipid delta(4)-desaturase DES1 isoform X1.
     
 0.521
DENND1B
DENN domain-containing protein 1B isoform X1.
      
 0.514
LOC111177292
Alpha-1-acid glycoprotein-like isoform X1.
      
 0.509
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.