Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SMSSpermine synthase. (476 aa)    
Predicted Functional Partners:
AMD1
S-adenosylmethionine decarboxylase proenzyme.
  
 
 0.983
SRM
Spermidine synthase isoform X1; Belongs to the spermidine/spermine synthase family.
  
 
0.970
MTAP
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
  
 
 0.968
SMOX
Spermine oxidase isoform X2.
     
 0.955
LACC1
Laccase domain-containing protein 1.
    
  0.901
MTRR
Methionine synthase reductase.
    
 
 0.879
LOC111162922
S-adenosylmethionine decarboxylase proenzyme-like.
  
 
 0.847
ODC1
Ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
  
 0.782
LOC111164713
LOW QUALITY PROTEIN: ornithine decarboxylase-like; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
  
 0.782
AGMAT
Agmatinase, mitochondrial isoform X1; Belongs to the arginase family.
  
 
 0.780
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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