TIMP1 protein (Delphinapterus leucas) - STRING interaction network

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Predicted Interactions

gene neighborhood

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textmining

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Score

TIMP1

Metalloproteinase inhibitor 1. (257 aa)

Predicted Functional Partners:

MMP9

0.988

MMP14

0.913

MMP1

0.908

MMP8

0.868

MMP2

0.838

LOC111167570

0.833

MMP7

0.807

MMP15

0.762

IL6

0.732

MMP20

0.731

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IL6	LOC111167570	Q9XT80	A0A2Y9MAX2	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]	Stromelysin-1-like.	0.632
IL6	MMP1	Q9XT80	A0A2Y9M3E9	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]	Interstitial collagenase isoform X1.	0.554
IL6	MMP2	Q9XT80	A0A2Y9M058	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]	72 kDa type IV collagenase.	0.543
IL6	MMP7	Q9XT80	A0A2Y9M7S1	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]	Matrilysin isoform X2.	0.458
IL6	MMP8	Q9XT80	A0A2Y9M5A1	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]	Neutrophil collagenase isoform X1.	0.484
IL6	MMP9	Q9XT80	A0A2Y9MNP1	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]	Matrix metalloproteinase-9.	0.746
IL6	TIMP1	Q9XT80	A0A2Y9M402	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]	Metalloproteinase inhibitor 1.	0.732
LOC111167570	IL6	A0A2Y9MAX2	Q9XT80	Stromelysin-1-like.	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]	0.632
LOC111167570	MMP1	A0A2Y9MAX2	A0A2Y9M3E9	Stromelysin-1-like.	Interstitial collagenase isoform X1.	0.971
LOC111167570	MMP14	A0A2Y9MAX2	A0A2Y9LVK1	Stromelysin-1-like.	Matrix metalloproteinase-14.	0.489
LOC111167570	MMP15	A0A2Y9MAX2	A0A2Y9LSF1	Stromelysin-1-like.	Matrix metalloproteinase-15 isoform X1.	0.422
LOC111167570	MMP20	A0A2Y9MAX2	A0A2Y9M3F8	Stromelysin-1-like.	Matrix metalloproteinase-20.	0.583
LOC111167570	MMP7	A0A2Y9MAX2	A0A2Y9M7S1	Stromelysin-1-like.	Matrilysin isoform X2.	0.606
LOC111167570	MMP8	A0A2Y9MAX2	A0A2Y9M5A1	Stromelysin-1-like.	Neutrophil collagenase isoform X1.	0.594
LOC111167570	MMP9	A0A2Y9MAX2	A0A2Y9MNP1	Stromelysin-1-like.	Matrix metalloproteinase-9.	0.961
LOC111167570	TIMP1	A0A2Y9MAX2	A0A2Y9M402	Stromelysin-1-like.	Metalloproteinase inhibitor 1.	0.833
MMP1	IL6	A0A2Y9M3E9	Q9XT80	Interstitial collagenase isoform X1.	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]	0.554
MMP1	LOC111167570	A0A2Y9M3E9	A0A2Y9MAX2	Interstitial collagenase isoform X1.	Stromelysin-1-like.	0.971
MMP1	MMP14	A0A2Y9M3E9	A0A2Y9LVK1	Interstitial collagenase isoform X1.	Matrix metalloproteinase-14.	0.492
MMP1	MMP15	A0A2Y9M3E9	A0A2Y9LSF1	Interstitial collagenase isoform X1.	Matrix metalloproteinase-15 isoform X1.	0.420