IER2 protein (Delphinapterus leucas) - STRING interaction network

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Score

IER2

Immediate early response gene 2 protein. (223 aa)

Predicted Functional Partners:

EGR1

0.749

EGR3

0.580

FOS

0.579

JUNB

0.558

FOSB

0.533

NR4A1

0.498

EGR2

0.481

CSRNP2

0.478

IER3

0.477

BTG2

0.451

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTG2	EGR1	A0A2Y9PRH6	A0A2Y9PCH3	Protein BTG2.	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	0.493
BTG2	EGR3	A0A2Y9PRH6	A0A2Y9M8U7	Protein BTG2.	Early growth response protein 3 isoform X1.	0.523
BTG2	FOS	A0A2Y9PRH6	A0A2Y9NGY2	Protein BTG2.	Proto-oncogene c-Fos.	0.505
BTG2	IER2	A0A2Y9PRH6	A0A2Y9M525	Protein BTG2.	Immediate early response gene 2 protein.	0.451
BTG2	JUNB	A0A2Y9PRH6	A0A2Y9LXN7	Protein BTG2.	Transcription factor jun-B.	0.442
BTG2	NR4A1	A0A2Y9PRH6	A0A2Y9NEY9	Protein BTG2.	Nuclear receptor subfamily 4 group A member 1.	0.530
CSRNP2	IER2	A0A2Y9N435	A0A2Y9M525	Cysteine/serine-rich nuclear protein 2.	Immediate early response gene 2 protein.	0.478
EGR1	BTG2	A0A2Y9PCH3	A0A2Y9PRH6	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	Protein BTG2.	0.493
EGR1	EGR2	A0A2Y9PCH3	A0A2Y9MGA1	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	E3 SUMO-protein ligase EGR2 isoform X1.	0.881
EGR1	EGR3	A0A2Y9PCH3	A0A2Y9M8U7	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	Early growth response protein 3 isoform X1.	0.644
EGR1	FOS	A0A2Y9PCH3	A0A2Y9NGY2	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	Proto-oncogene c-Fos.	0.923
EGR1	FOSB	A0A2Y9PCH3	A0A2Y9P758	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	Protein fosB isoform X1.	0.873
EGR1	IER2	A0A2Y9PCH3	A0A2Y9M525	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	Immediate early response gene 2 protein.	0.749
EGR1	JUNB	A0A2Y9PCH3	A0A2Y9LXN7	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	Transcription factor jun-B.	0.658
EGR1	NR4A1	A0A2Y9PCH3	A0A2Y9NEY9	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	Nuclear receptor subfamily 4 group A member 1.	0.678
EGR2	EGR1	A0A2Y9MGA1	A0A2Y9PCH3	E3 SUMO-protein ligase EGR2 isoform X1.	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	0.881
EGR2	EGR3	A0A2Y9MGA1	A0A2Y9M8U7	E3 SUMO-protein ligase EGR2 isoform X1.	Early growth response protein 3 isoform X1.	0.975
EGR2	FOS	A0A2Y9MGA1	A0A2Y9NGY2	E3 SUMO-protein ligase EGR2 isoform X1.	Proto-oncogene c-Fos.	0.757
EGR2	FOSB	A0A2Y9MGA1	A0A2Y9P758	E3 SUMO-protein ligase EGR2 isoform X1.	Protein fosB isoform X1.	0.720
EGR2	IER2	A0A2Y9MGA1	A0A2Y9M525	E3 SUMO-protein ligase EGR2 isoform X1.	Immediate early response gene 2 protein.	0.481