Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CUL4Bcullin-4B isoform X1; Belongs to the cullin family. (904 aa)    
Predicted Functional Partners:
DDB1
DNA damage-binding protein 1.
   
 0.982
DCAF1
DDB1- and CUL4-associated factor 1 isoform X1.
   
 0.956
RBX1
E3 ubiquitin-protein ligase RBX1.
    
 0.946
DDB2
DNA damage-binding protein 2 isoform X1.
    
 0.921
CUL4A
cullin-4A; Belongs to the cullin family.
  
  
0.914
DCAF11
DDB1- and CUL4-associated factor 11; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat LEC14B family.
    
 0.912
ERCC8
DNA excision repair protein ERCC-8 isoform X1.
    
 0.905
LOC111175787
LOW QUALITY PROTEIN: cullin-4B-like; Belongs to the cullin family.
  
  
 
0.900
WDTC1
WD and tetratricopeptide repeats protein 1 isoform X1.
    
 0.892
CRBN
Protein cereblon.
    
 0.887
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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