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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IZUMO1RSperm-egg fusion protein Juno. (269 aa)    
Predicted Functional Partners:
IZUMO1
Izumo sperm-egg fusion protein 1 isoform X1.
    
 
 0.876
MASP2
Mannan-binding lectin serine protease 2 isoform X1; Belongs to the peptidase S1 family.
    
 0.519
IKZF2
Zinc finger protein Helios isoform X1.
      
 0.514
PRNP
Major prion protein; Belongs to the prion family.
    
 0.447
CTLA4
Cytotoxic T-lymphocyte protein 4 isoform X1.
     
 0.441
ALB
Serum albumin.
      
 0.435
TFRC
Transferrin receptor protein 1 isoform X1.
      
 0.434
SLC46A1
Proton-coupled folate transporter.
      
 0.434
ICOS
Inducible T-cell costimulator isoform X1.
   
  
 0.420
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.