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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DHX58Probable ATP-dependent RNA helicase DHX58 isoform X1. (680 aa)    
Predicted Functional Partners:
IFIH1
Interferon-induced helicase C domain-containing protein 1.
   
0.965
USP18
Ubl carboxyl-terminal hydrolase 18 isoform X1; Belongs to the peptidase C19 family.
   
 
 0.879
OASL
2'-5'-oligoadenylate synthase-like protein isoform X1.
   
 0.817
MAVS
Mitochondrial antiviral-signaling protein isoform X1.
    
 0.812
IRF7
Interferon regulatory factor 7 isoform X1.
   
 0.759
FANCG
Fanconi anemia group G protein isoform X1.
    
 0.754
FANCL
E3 ubiquitin-protein ligase FANCL isoform X1.
    
 0.751
FANCF
Fanconi anemia group F protein.
    
 0.750
FANCB
Fanconi anemia group B protein isoform X1.
   
 0.746
FANCC
Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
    
 0.735
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.