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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDK12Cyclin-dependent kinase 12 isoform X1. (1490 aa)    
Predicted Functional Partners:
CCNK
cyclin-K; Belongs to the cyclin family.
   
 0.999
POLR2A
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.892
CCNT2
cyclin-T2 isoform X1; Belongs to the cyclin family.
   
 0.862
SUPT5H
Transcription elongation factor SPT5.
    
 0.851
CCNT1
cyclin-T1; Belongs to the cyclin family.
   
 0.847
CUNH6orf15
Uncharacterized protein C6orf15 homolog.
    
 0.760
CCNH
cyclin-H; Belongs to the cyclin family.
    
 0.760
CCNQ
Cyclin-related protein FAM58A isoform X1; Belongs to the cyclin family.
   
 0.746
ERCC3
TFIIH basal transcription factor complex helicase XPB subunit isoform X1.
   
 
 0.707
SUPT4H1
Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.
    
 0.704
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.