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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSD17B73-keto-steroid reductase isoform X2. (334 aa)    
Predicted Functional Partners:
MSMO1
Methylsterol monooxygenase 1; Belongs to the sterol desaturase family.
   
 0.991
NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; Belongs to the 3-beta-HSD family.
   
 0.989
LSS
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
   
 
 0.978
LOC111180826
Lanosterol 14-alpha demethylase isoform X1; Belongs to the cytochrome P450 family.
   
 
 0.973
SC5D
Lathosterol oxidase; Belongs to the sterol desaturase family.
   
 0.972
DHCR24
Delta(24)-sterol reductase.
   
 
 0.963
FDFT1
Squalene synthase isoform X1.
   
 
 0.956
HSD17B1
Estradiol 17-beta-dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.947
EBP
3-beta-hydroxysteroid-Delta(8), Delta(7)-isomerase.
   
 
 0.947
ERG28
Probable ergosterol biosynthetic protein 28 isoform X1.
   
 
 0.947
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.