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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOK2Docking protein 2. (411 aa)    
Predicted Functional Partners:
TEK
Angiopoietin-1 receptor.
    
 0.830
CSK
Tyrosine-protein kinase.
   
 0.716
CUNH6orf58
Protein LEG1 homolog.
      
 0.696
TMED1
Transmembrane emp24 domain-containing protein 1.
      
 0.649
TIE1
Tyrosine-protein kinase receptor Tie-1 isoform X1.
    
 0.648
GFRA2
GDNF family receptor alpha; Belongs to the GDNFR family.
     
 0.631
LYN
Tyrosine-protein kinase.
   
 0.626
RET
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
    
 0.615
RASA1
Ras GTPase-activating protein 1 isoform X1.
   
 
 0.608
LOC111168242
Protein LEG1 homolog.
      
 0.582
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.