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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC111168503Histone H1t. (226 aa)    
Predicted Functional Partners:
LOC111168978
Histone H1oo.
   
 0.712
LRWD1
Leucine-rich repeat and WD repeat-containing protein 1 isoform X1.
      
 0.683
SYCP3
LOW QUALITY PROTEIN: synaptonemal complex protein 3.
    
 
 0.528
NAP1L4
Nucleosome assembly protein 1-like 4 isoform X1; Belongs to the nucleosome assembly protein (NAP) family.
    
 
 0.515
MTIF3
LOW QUALITY PROTEIN: translation initiation factor IF-3, mitochondrial.
      
 0.505
CDK2
Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily.
   
 0.495
LOC111168531
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.494
LOC111168536
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.494
SMARCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E, member 1.
   
  
 0.442
LOC111166024
ATPase SWSAP1-like.
      
 0.438
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.