Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
BABAM1BRISC and BRCA1-A complex member 1. (330 aa)    
Predicted Functional Partners:
UIMC1
BRCA1-A complex subunit RAP80 isoform X1.
    
 0.999
BRCC3
Lys-63-specific deubiquitinase BRCC36 isoform X1.
   
 0.999
BABAM2
BRISC and BRCA1-A complex member 2 isoform X1.
    
 0.999
ABRAXAS2
BRISC complex subunit Abraxas 2.
    
 0.997
BRCA1
Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]
    
 0.987
BARD1
BRCA1-associated RING domain protein 1 isoform X1.
    
 0.966
ABRAXAS1
BRCA1-A complex subunit Abraxas 1.
    
  0.911
TNKS2
Poly [ADP-ribose] polymerase.
    
 0.903
TNKS
Poly [ADP-ribose] polymerase.
    
 0.877
CUNH9orf85
LOW QUALITY PROTEIN: uncharacterized protein C9orf85 homolog.
    
   0.778
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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