| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABAT | ACLY | A0A2Y9LGN2 | A0A2Y9M2D9 | 4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | 0.459 |
| ABAT | ALDH5A1 | A0A2Y9LGN2 | A0A2Y9MAM6 | 4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.986 |
| ACLY | ABAT | A0A2Y9M2D9 | A0A2Y9LGN2 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | 4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.459 |
| ACLY | ALDH5A1 | A0A2Y9M2D9 | A0A2Y9MAM6 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.877 |
| ACLY | CS | A0A2Y9M2D9 | A0A2Y9MYL6 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Citrate synthase; Belongs to the citrate synthase family. | 0.993 |
| ACLY | IDH1 | A0A2Y9M2D9 | A0A2Y9N1U7 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.786 |
| ACLY | IDH2 | A0A2Y9M2D9 | A0A2Y9MKY3 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.788 |
| ACLY | IDH3A | A0A2Y9M2D9 | A0A2Y9NXN6 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. | 0.447 |
| ACLY | MDH2 | A0A2Y9M2D9 | A0A2Y9PKE8 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Malate dehydrogenase. | 0.967 |
| ACLY | OGDH | A0A2Y9M2D9 | A0A2Y9PZR3 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | 2-oxoglutarate dehydrogenase, mitochondrial isoform X1. | 0.830 |
| ACLY | OGDHL | A0A2Y9M2D9 | A0A2Y9MGX7 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | 2-oxoglutarate dehydrogenase-like, mitochondrial isoform X1. | 0.802 |
| ACLY | PC | A0A2Y9M2D9 | A0A2Y9PJC3 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.950 |
| ALDH5A1 | ABAT | A0A2Y9MAM6 | A0A2Y9LGN2 | Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.986 |
| ALDH5A1 | ACLY | A0A2Y9MAM6 | A0A2Y9M2D9 | Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | 0.877 |
| ALDH5A1 | CS | A0A2Y9MAM6 | A0A2Y9MYL6 | Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Citrate synthase; Belongs to the citrate synthase family. | 0.903 |
| ALDH5A1 | IDH1 | A0A2Y9MAM6 | A0A2Y9N1U7 | Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.849 |
| ALDH5A1 | IDH2 | A0A2Y9MAM6 | A0A2Y9MKY3 | Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.849 |
| ALDH5A1 | IDH3A | A0A2Y9MAM6 | A0A2Y9NXN6 | Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. | 0.847 |
| ALDH5A1 | MDH2 | A0A2Y9MAM6 | A0A2Y9PKE8 | Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Malate dehydrogenase. | 0.869 |
| ALDH5A1 | OGDH | A0A2Y9MAM6 | A0A2Y9PZR3 | Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 2-oxoglutarate dehydrogenase, mitochondrial isoform X1. | 0.885 |