ENTPD3 protein (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ENTPD3

Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family. (529 aa)

Predicted Functional Partners:

ENPP3

0.931

ENTPD5

0.926

RRM1

0.923

CMPK1

0.923

TK2

0.923

UCK1

0.921

ENTPD6

0.921

CTPS2

0.920

CTPS1

0.920

CANT1

0.919

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CANT1	ENPP3	A0A2Y9PQM2	A0A2Y9LZG3	Soluble calcium-activated nucleotidase 1.	Ectonucleotide pyrophosphatase/phosphodiesterase family member 3.	0.910
CANT1	ENTPD3	A0A2Y9PQM2	A0A2Y9MB36	Soluble calcium-activated nucleotidase 1.	Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family.	0.919
CANT1	ENTPD5	A0A2Y9PQM2	A0A2Y9NH71	Soluble calcium-activated nucleotidase 1.	Ectonucleoside triphosphate diphosphohydrolase 5; Belongs to the GDA1/CD39 NTPase family.	0.916
CANT1	ENTPD6	A0A2Y9PQM2	A0A2Y9Q3D1	Soluble calcium-activated nucleotidase 1.	Ectonucleoside triphosphate diphosphohydrolase 6 isoform X1; Belongs to the GDA1/CD39 NTPase family.	0.925
CANT1	RRM1	A0A2Y9PQM2	A0A2Y9MH30	Soluble calcium-activated nucleotidase 1.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.925
CANT1	UCK1	A0A2Y9PQM2	A0A2Y9NML8	Soluble calcium-activated nucleotidase 1.	Uridine-cytidine kinase; Belongs to the uridine kinase family.	0.925
CMPK1	ENPP3	A0A2Y9NAT4	A0A2Y9LZG3	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Ectonucleotide pyrophosphatase/phosphodiesterase family member 3.	0.906
CMPK1	ENTPD3	A0A2Y9NAT4	A0A2Y9MB36	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family.	0.923
CMPK1	RRM1	A0A2Y9NAT4	A0A2Y9MH30	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.945
CMPK1	TK2	A0A2Y9NAT4	A0A2Y9PA18	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Thymidine kinase 2, mitochondrial isoform X1.	0.941
CMPK1	UCK1	A0A2Y9NAT4	A0A2Y9NML8	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Uridine-cytidine kinase; Belongs to the uridine kinase family.	0.950
CTPS1	CTPS2	A0A2Y9NP77	A0A2Y9M9M9	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.953
CTPS1	ENPP3	A0A2Y9NP77	A0A2Y9LZG3	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Ectonucleotide pyrophosphatase/phosphodiesterase family member 3.	0.907
CTPS1	ENTPD3	A0A2Y9NP77	A0A2Y9MB36	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family.	0.920
CTPS1	RRM1	A0A2Y9NP77	A0A2Y9MH30	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.425
CTPS1	UCK1	A0A2Y9NP77	A0A2Y9NML8	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Uridine-cytidine kinase; Belongs to the uridine kinase family.	0.556
CTPS2	CTPS1	A0A2Y9M9M9	A0A2Y9NP77	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.953
CTPS2	ENPP3	A0A2Y9M9M9	A0A2Y9LZG3	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Ectonucleotide pyrophosphatase/phosphodiesterase family member 3.	0.906
CTPS2	ENTPD3	A0A2Y9M9M9	A0A2Y9MB36	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family.	0.920
CTPS2	UCK1	A0A2Y9M9M9	A0A2Y9NML8	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Uridine-cytidine kinase; Belongs to the uridine kinase family.	0.567