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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERCC6L2DNA excision repair protein ERCC-6-like 2 isoform X1. (1626 aa)    
Predicted Functional Partners:
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.740
RUVBL1
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
    
 0.718
FANCM
Fanconi anemia group M protein isoform X1.
   
 0.718
RAD18
E3 ubiquitin-protein ligase RAD18.
   
 0.698
ACTR5
Actin-related protein 5; Belongs to the actin family.
    
 0.671
ACTL6A
Actin-like protein 6A; Belongs to the actin family.
   
 0.646
ACTL6B
Actin-like protein 6B isoform X1; Belongs to the actin family.
   
 0.646
INO80C
INO80 complex subunit C isoform X1.
    
 0.635
CUNH7orf49
Modulator of retrovirus infection homolog isoform X1.
    
 
 0.631
MAD2L1
Mitotic spindle assembly checkpoint protein MAD2A.
   
 0.622
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.