close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
USF1Upstream stimulatory factor 1 isoform X1. (310 aa)    
Predicted Functional Partners:
USF2
Upstream stimulatory factor 2.
  
 
0.983
EP300
Histone acetyltransferase p300.
    
 0.923
SP1
Transcription factor Sp1.
    
 0.835
GTF2I
General transcription factor II-I isoform X1.
    
 
 0.651
CREBBP
CREB-binding protein isoform X1.
    
 0.638
MLANA
Melanoma antigen recognized by T-cells 1.
      
 0.610
ESR1
Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
    
 0.579
YY1
Transcriptional repressor protein YY1.
    
 0.579
CEBPB
CCAAT/enhancer-binding protein.
   
 
 0.554
TYR
Tyrosinase.
    
 0.539
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.