Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
USF1Upstream stimulatory factor 1 isoform X1. (310 aa)    
Predicted Functional Partners:
USF2
Upstream stimulatory factor 2.
   
 0.994
GTF2I
General transcription factor II-I isoform X1.
    
 
 0.882
EP300
Histone acetyltransferase p300.
    
 0.826
SP1
Transcription factor Sp1.
    
 0.789
MED1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
     
  0.774
FOSL1
Fos-related antigen 1.
    
 
 0.772
MAPK14
Mitogen-activated protein kinase.
    
 0.679
MAPK11
Mitogen-activated protein kinase.
    
 0.679
ADAMTS7
A disintegrin and metalloproteinase with thrombospondin motifs 7.
   
 
 0.669
ADAMTS12
A disintegrin and metalloproteinase with thrombospondin motifs 12 isoform X1.
   
 
 0.669
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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