close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRTC3CREB-regulated transcription coactivator 3 isoform X1. (619 aa)    
Predicted Functional Partners:
CRTC2
CREB-regulated transcription coactivator 2 isoform X1.
     
0.908
CRTC1
CREB-regulated transcription coactivator 1 isoform X1.
     
0.908
CREB1
Cyclic AMP-responsive element-binding protein 1 isoform X1.
    
 0.701
SIK2
Serine/threonine-protein kinase SIK2 isoform X1.
    
 
 0.699
SIK3
Serine/threonine-protein kinase SIK3 isoform X1.
    
 
 0.638
SIK1
Serine/threonine-protein kinase SIK1.
    
 
 0.632
ATF1
Cyclic AMP-dependent transcription factor ATF-1 isoform X1.
    
 0.537
MBTPS2
Membrane-bound transcription factor site-2 protease isoform X1.
     
 0.464
MBTPS1
Membrane-bound transcription factor site-1 protease isoform X1.
   
 
 0.449
STAR
Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.
      
 0.437
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.