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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IGSF8Immunoglobulin superfamily member 8 isoform X2. (629 aa)    
Predicted Functional Partners:
PLCL1
Phosphoinositide phospholipase C.
      
 0.714
OAZ2
LOW QUALITY PROTEIN: ornithine decarboxylase antizyme 2.
      
 0.707
PIF1
ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...]
      
 0.702
DNAJB13
dnaJ homolog subfamily B member 13.
      
 0.700
ACBD6
acyl-CoA-binding domain-containing protein 6 isoform X1.
      
 0.676
BRINP2
BMP/retinoic acid-inducible neural-specific protein 2 isoform X1.
      
 0.611
LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1 isoform X1.
      
 0.605
CD82
Tetraspanin.
    
 
 0.559
CD81
Tetraspanin.
    
 
 0.556
TMEM237
Transmembrane protein 237 isoform X1.
      
 0.551
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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