| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADSL | ADSS | A0A2Y9Q4W5 | A0A2Y9NM91 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.998 |
| ADSL | ADSSL1 | A0A2Y9Q4W5 | A0A2Y9NQM8 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.996 |
| ADSL | ATIC | A0A2Y9Q4W5 | A0A2Y9MQY2 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Bifunctional purine biosynthesis protein PURH isoform X1. | 0.999 |
| ADSL | GART | A0A2Y9Q4W5 | A0A2Y9LTB9 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.999 |
| ADSL | GMPS | A0A2Y9Q4W5 | A0A2Y9N9A0 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GMP synthase [glutamine-hydrolyzing]. | 0.795 |
| ADSL | LOC111169417 | A0A2Y9Q4W5 | A0A2Y9MEB9 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Multifunctional protein ADE2 isoform X2. | 0.999 |
| ADSL | MTHFD1L | A0A2Y9Q4W5 | A0A2Y9LYY0 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Monofunctional C1-tetrahydrofolate synthase, mitochondrial isoform X1. | 0.466 |
| ADSL | PPAT | A0A2Y9Q4W5 | A0A2Y9MC83 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.977 |
| ADSS | ADSL | A0A2Y9NM91 | A0A2Y9Q4W5 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.998 |
| ADSS | ADSSL1 | A0A2Y9NM91 | A0A2Y9NQM8 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.901 |
| ADSS | ATIC | A0A2Y9NM91 | A0A2Y9MQY2 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Bifunctional purine biosynthesis protein PURH isoform X1. | 0.992 |
| ADSS | GART | A0A2Y9NM91 | A0A2Y9LTB9 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.983 |
| ADSS | GMPS | A0A2Y9NM91 | A0A2Y9N9A0 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | GMP synthase [glutamine-hydrolyzing]. | 0.827 |
| ADSS | LOC111169417 | A0A2Y9NM91 | A0A2Y9MEB9 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Multifunctional protein ADE2 isoform X2. | 0.927 |
| ADSS | PPAT | A0A2Y9NM91 | A0A2Y9MC83 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.663 |
| ADSSL1 | ADSL | A0A2Y9NQM8 | A0A2Y9Q4W5 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.996 |
| ADSSL1 | ADSS | A0A2Y9NQM8 | A0A2Y9NM91 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.901 |
| ADSSL1 | ATIC | A0A2Y9NQM8 | A0A2Y9MQY2 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Bifunctional purine biosynthesis protein PURH isoform X1. | 0.987 |
| ADSSL1 | GART | A0A2Y9NQM8 | A0A2Y9LTB9 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.983 |
| ADSSL1 | GMPS | A0A2Y9NQM8 | A0A2Y9N9A0 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | GMP synthase [glutamine-hydrolyzing]. | 0.529 |