close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CD247T-cell surface glycoprotein CD3 zeta chain isoform X1. (185 aa)    
Predicted Functional Partners:
CD3G
T-cell surface glycoprotein CD3 gamma chain.
   
 0.999
LOC111187417
Tyrosine-protein kinase.
   
 0.999
CD3E
T-cell surface glycoprotein CD3 epsilon chain.
   
 0.998
CD3D
T-cell surface glycoprotein CD3 delta chain.
   
 0.997
SYK
Tyrosine-protein kinase.
   
 0.990
LOC111170413
Low affinity immunoglobulin gamma Fc region receptor III-like isoform X1.
     
 0.986
NCR3
Natural cytotoxicity triggering receptor 3.
   
 0.966
CD8A
T-cell surface glycoprotein CD8 alpha chain isoform X1.
   
 
 0.962
PTPN6
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
   
 0.959
LOC111178927
HLA class II histocompatibility antigen, DQ alpha 2 chain; Belongs to the MHC class II family.
   
 
 0.955
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
Server load: low (20%) [HD]