WIPI2 protein (Delphinapterus leucas) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

WIPI2

WD repeat domain phosphoinositide-interacting protein 2 isoform X1. (436 aa)

Predicted Functional Partners:

ATG16L1

0.997

ATG2A

0.981

ATG16L2

0.979

ATG2B

0.975

WIPI1

0.950

ATG12

0.938

ATG5

0.932

ATG14

0.853

ULK2

0.811

ATG7

0.798

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG12	ATG14	A0A2Y9PU20	A0A2Y9NAF1	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Beclin 1-associated autophagy-related key regulator.	0.861
ATG12	ATG16L1	A0A2Y9PU20	A0A2Y9MP10	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy-related protein 16-1 isoform X1.	0.999
ATG12	ATG16L2	A0A2Y9PU20	A0A2Y9PRJ0	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy-related protein 16-2 isoform X1.	0.993
ATG12	ATG2A	A0A2Y9PU20	A0A2Y9PW25	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy-related protein 2 homolog A isoform X1.	0.505
ATG12	ATG2B	A0A2Y9PU20	A0A2Y9NCI5	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy-related protein 2 homolog B isoform X1.	0.487
ATG12	ATG5	A0A2Y9PU20	A0A2Y9LPY0	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
ATG12	ATG7	A0A2Y9PU20	A0A2Y9MHI4	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.999
ATG12	ULK2	A0A2Y9PU20	A0A2Y9MC66	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Serine/threonine-protein kinase ULK2 isoform X1.	0.870
ATG12	WIPI1	A0A2Y9PU20	A0A2Y9PI92	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	WD repeat domain phosphoinositide-interacting protein 1 isoform X1.	0.873
ATG12	WIPI2	A0A2Y9PU20	A0A2Y9MFS8	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	WD repeat domain phosphoinositide-interacting protein 2 isoform X1.	0.938
ATG14	ATG12	A0A2Y9NAF1	A0A2Y9PU20	Beclin 1-associated autophagy-related key regulator.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.861
ATG14	ATG16L1	A0A2Y9NAF1	A0A2Y9MP10	Beclin 1-associated autophagy-related key regulator.	Autophagy-related protein 16-1 isoform X1.	0.822
ATG14	ATG16L2	A0A2Y9NAF1	A0A2Y9PRJ0	Beclin 1-associated autophagy-related key regulator.	Autophagy-related protein 16-2 isoform X1.	0.681
ATG14	ATG2A	A0A2Y9NAF1	A0A2Y9PW25	Beclin 1-associated autophagy-related key regulator.	Autophagy-related protein 2 homolog A isoform X1.	0.507
ATG14	ATG2B	A0A2Y9NAF1	A0A2Y9NCI5	Beclin 1-associated autophagy-related key regulator.	Autophagy-related protein 2 homolog B isoform X1.	0.502
ATG14	ATG5	A0A2Y9NAF1	A0A2Y9LPY0	Beclin 1-associated autophagy-related key regulator.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.858
ATG14	ATG7	A0A2Y9NAF1	A0A2Y9MHI4	Beclin 1-associated autophagy-related key regulator.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.641
ATG14	ULK2	A0A2Y9NAF1	A0A2Y9MC66	Beclin 1-associated autophagy-related key regulator.	Serine/threonine-protein kinase ULK2 isoform X1.	0.991
ATG14	WIPI1	A0A2Y9NAF1	A0A2Y9PI92	Beclin 1-associated autophagy-related key regulator.	WD repeat domain phosphoinositide-interacting protein 1 isoform X1.	0.812
ATG14	WIPI2	A0A2Y9NAF1	A0A2Y9MFS8	Beclin 1-associated autophagy-related key regulator.	WD repeat domain phosphoinositide-interacting protein 2 isoform X1.	0.853