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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGAP45Rho GTPase-activating protein 45 isoform X1. (1171 aa)    
Predicted Functional Partners:
SBNO2
Protein strawberry notch homolog 2 isoform X1.
      
 0.762
POLR2E
DNA-directed RNA polymerases I, II, and III subunit RPABC1.
      
 0.694
DNMBP
Dynamin-binding protein isoform X1.
    
 
 0.561
ARHGEF37
Rho guanine nucleotide exchange factor 37 isoform X1.
    
 
 0.561
CDC42
Cell division control protein 42 homolog isoform X2.
   
 0.538
FCHSD1
F-BAR and double SH3 domains protein 1 isoform X1.
    
 0.535
RASIP1
Ras-interacting protein 1.
    
 0.526
UBASH3A
Ubiquitin-associated and SH3 domain-containing protein A isoform X1.
      
 0.517
DNTTIP2
Deoxynucleotidyltransferase terminal-interacting protein 2.
      
 0.515
MON1B
Vacuolar fusion protein MON1 homolog B.
      
 0.515
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.