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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa)    
Predicted Functional Partners:
IL12A
Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC.
    
 0.993
IL12RB1
Interleukin-12 receptor subunit beta-1 isoform X1.
    
 0.990
IL12RB2
Interleukin-12 receptor subunit beta-2 isoform X1.
   
 
 0.942
P4HB
Protein disulfide-isomerase.
   
  0.789
IFNGR1
Interferon gamma receptor 1.
  
  
 0.780
IL27RA
Interleukin-27 receptor subunit alpha isoform X1.
   
 
 0.769
IL23R
Interleukin-23 receptor.
   
 
 0.769
IL6ST
Interleukin-6 receptor subunit beta.
   
 
 0.769
IL2RA
Interleukin-2 receptor subunit alpha.
   
 
 0.735
IL6R
Interleukin-6 receptor subunit alpha isoform X1.
  
 
0.712
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.