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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F8Coagulation factor VIII; Belongs to the multicopper oxidase family. (2152 aa)    
Predicted Functional Partners:
VWF
Von Willebrand factor.
    
 0.987
PROC
Vitamin K-dependent protein C.
    
 0.965
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
    
 0.814
F10
Coagulation factor X isoform X1.
   
 0.760
F9
Coagulation factor IX.
   
 0.741
PROS1
Vitamin K-dependent protein S.
   
 0.659
F7
Coagulation factor VII isoform X1.
   
 0.640
F5
Coagulation factor V isoform X1; Belongs to the multicopper oxidase family.
  
  
0.634
SERPINC1
antithrombin-III isoform X1; Belongs to the serpin family.
   
 0.578
MCFD2
Multiple coagulation factor deficiency protein 2.
     
 0.566
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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