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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ELF4ETS-related transcription factor Elf-4 isoform X1. (662 aa)    
Predicted Functional Partners:
LRRC30
Leucine-rich repeat-containing protein 30.
      
 0.703
INSR
Tyrosine-protein kinase receptor.
    
 0.532
ESPNL
Espin-like protein.
    
 
 0.516
LOC111172488
Cytochrome P450 26C1; Belongs to the cytochrome P450 family.
    
 
 0.514
LOC111164523
Integrator complex subunit 6-like isoform X1.
      
 0.495
PRR7
Proline-rich protein 7.
      
 0.491
CSF2
Granulocyte-macrophage colony-stimulating factor.
  
   
 0.464
TBK1
Serine/threonine-protein kinase TBK1.
    
 0.458
RUNX1
Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
    
 0.450
RNF141
RING finger protein 141.
   
  
 0.443
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.