Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC111170861Aromatase-like. (388 aa)    
Predicted Functional Partners:
LOC111179902
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; Belongs to the 3-beta-HSD family.
   
 0.956
HSD17B3
Testosterone 17-beta-dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.950
HSD17B2
Estradiol 17-beta-dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 0.930
SRD5A1
3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)).
     
 0.926
LOC111168146
LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 2B4-like.
   
 0.925
LOC111171956
UDP-glucuronosyltransferase 1-3-like isoform X1; Belongs to the UDP-glycosyltransferase family.
   
 0.925
LOC111172355
Steroid 17-alpha-hydroxylase/17,20 lyase; Belongs to the cytochrome P450 family.
   
 0.925
SULT1E1
Sulfotransferase; Belongs to the sulfotransferase 1 family.
   
 
 0.921
SRD5A3
Polyprenol reductase.
     
 0.920
HSD17B8
Estradiol 17-beta-dehydrogenase 8 isoform X1.
   
 
 0.920
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
Server load: low (22%) [HD]