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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLF8Krueppel-like factor 8 isoform X1. (393 aa)    
Predicted Functional Partners:
CTBP2
C-terminal-binding protein 2 isoform X1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 
 0.634
CTBP1
C-terminal-binding protein 1 isoform X1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 
 0.548
HUWE1
E3 ubiquitin-protein ligase HUWE1.
    
 
 0.518
KLF17
Krueppel-like factor 17.
      
0.514
KLF14
Krueppel-like factor 14.
      
0.514
ZC3H12B
Probable ribonuclease ZC3H12B.
    
 
 0.503
KLF16
Krueppel-like factor 16.
      
0.497
KLF10
Krueppel-like factor 10 isoform X2.
   
  
0.445
ZEB1
Zinc finger E-box-binding homeobox 1 isoform X2.
    
 
0.443
SOX15
Protein SOX-15.
    
 0.415
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.