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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC111171351Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (113 aa)    
Predicted Functional Partners:
LOC111170644
BOLA class I histocompatibility antigen, alpha chain BL3-7-like isoform X1; Belongs to the MHC class I family.
   
 0.984
LOC111166690
H-2 class I histocompatibility antigen, Q10 alpha chain-like isoform X1; Belongs to the MHC class I family.
   
 0.977
LOC111167107
T-cell surface glycoprotein CD1b-2-like.
    
 0.912
WRN
Werner syndrome ATP-dependent helicase isoform X1.
   
 0.902
FANCM
Fanconi anemia group M protein isoform X1.
   
 0.890
RPA1
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
   
 0.885
RPA3
Replication protein A 14 kDa subunit isoform X1.
   
 0.882
PDIA3
Protein disulfide-isomerase.
    
 0.808
RAD52
DNA repair protein RAD52 homolog isoform X1.
    
 0.732
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.729
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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