node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APAF1 | BAK1 | A0A2Y9QDI9 | A0A2Y9NQC8 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Bcl-2 homologous antagonist/killer isoform X1. | 0.712 |
APAF1 | BAX | A0A2Y9QDI9 | A0A2Y9P6K0 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Apoptosis regulator BAX isoform X2. | 0.603 |
APAF1 | BCL2 | A0A2Y9QDI9 | A0A2Y9P9P5 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Apoptosis regulator Bcl-2. | 0.864 |
APAF1 | BCL2L1 | A0A2Y9QDI9 | A0A2Y9PZ68 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Bcl-2-like protein 1 isoform X1. | 0.706 |
APAF1 | CASP3 | A0A2Y9QDI9 | A0A2Y9N0H4 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Caspase-3 isoform X1; Belongs to the peptidase C14A family. | 0.991 |
APAF1 | CASP9 | A0A2Y9QDI9 | A0A2Y9Q4X2 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Caspase-9; Belongs to the peptidase C14A family. | 0.999 |
APAF1 | HTRA2 | A0A2Y9QDI9 | A0A2Y9M985 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Serine protease HTRA2, mitochondrial. | 0.489 |
APAF1 | LOC111174031 | A0A2Y9QDI9 | A0A2Y9NFC7 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.995 |
BAK1 | APAF1 | A0A2Y9NQC8 | A0A2Y9QDI9 | Bcl-2 homologous antagonist/killer isoform X1. | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | 0.712 |
BAK1 | BAX | A0A2Y9NQC8 | A0A2Y9P6K0 | Bcl-2 homologous antagonist/killer isoform X1. | Apoptosis regulator BAX isoform X2. | 0.975 |
BAK1 | BCL2 | A0A2Y9NQC8 | A0A2Y9P9P5 | Bcl-2 homologous antagonist/killer isoform X1. | Apoptosis regulator Bcl-2. | 0.978 |
BAK1 | BCL2L1 | A0A2Y9NQC8 | A0A2Y9PZ68 | Bcl-2 homologous antagonist/killer isoform X1. | Bcl-2-like protein 1 isoform X1. | 0.993 |
BAK1 | CASP3 | A0A2Y9NQC8 | A0A2Y9N0H4 | Bcl-2 homologous antagonist/killer isoform X1. | Caspase-3 isoform X1; Belongs to the peptidase C14A family. | 0.599 |
BAK1 | CASP9 | A0A2Y9NQC8 | A0A2Y9Q4X2 | Bcl-2 homologous antagonist/killer isoform X1. | Caspase-9; Belongs to the peptidase C14A family. | 0.597 |
BAK1 | LOC111174031 | A0A2Y9NQC8 | A0A2Y9NFC7 | Bcl-2 homologous antagonist/killer isoform X1. | Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.967 |
BAX | APAF1 | A0A2Y9P6K0 | A0A2Y9QDI9 | Apoptosis regulator BAX isoform X2. | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | 0.603 |
BAX | BAK1 | A0A2Y9P6K0 | A0A2Y9NQC8 | Apoptosis regulator BAX isoform X2. | Bcl-2 homologous antagonist/killer isoform X1. | 0.975 |
BAX | BCL2 | A0A2Y9P6K0 | A0A2Y9P9P5 | Apoptosis regulator BAX isoform X2. | Apoptosis regulator Bcl-2. | 0.960 |
BAX | BCL2L1 | A0A2Y9P6K0 | A0A2Y9PZ68 | Apoptosis regulator BAX isoform X2. | Bcl-2-like protein 1 isoform X1. | 0.943 |
BAX | CASP3 | A0A2Y9P6K0 | A0A2Y9N0H4 | Apoptosis regulator BAX isoform X2. | Caspase-3 isoform X1; Belongs to the peptidase C14A family. | 0.594 |