STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HRH2Histamine H2 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (401 aa)    
Predicted Functional Partners:
GNAS
Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1.
    
 0.953
GNAL
Guanine nucleotide-binding protein G(Olf) subunit alpha isoform X2.
    
 0.838
OGG1
N-glycosylase/DNA lyase isoform X1.
    
 
 0.732
GAST
Gastrin.
   
 0.702
ATP4A
Sodium/potassium-transporting ATPase subunit alpha.
      
 0.615
INS
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 
 0.581
SSTR4
LOW QUALITY PROTEIN: somatostatin receptor type 4.
   
0.566
CREB1
Cyclic AMP-responsive element-binding protein 1 isoform X1.
    
 
 0.520
HDC
Histidine decarboxylase isoform X1.
      
 0.514
TM4SF5
Transmembrane 4 L6 family member 5 isoform X1.
   
  
 0.442
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.