STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHRAryl hydrocarbon receptor; Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing [...] (845 aa)    
Predicted Functional Partners:
ARNT
Aryl hydrocarbon receptor nuclear translocator isoform X1.
   
0.999
AIP
AH receptor-interacting protein isoform X1.
    
 0.999
HSP90AA1
Heat shock protein HSP 90-alpha.
    
 0.998
HSP90AB1
Heat shock protein HSP 90-beta.
    
 0.998
AIPL1
Aryl-hydrocarbon-interacting protein-like 1.
    
 0.972
ARNT2
Aryl hydrocarbon receptor nuclear translocator 2 isoform X1.
   
0.959
PTGES3
Prostaglandin E synthase 3 isoform X1.
    
  0.950
TSC1
Hamartin.
    
 0.753
TRAP1
Heat shock protein 75 kDa, mitochondrial.
    
 0.753
ARNTL
Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X1.
   
0.662
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
Server load: low (14%) [HD]