STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCM2Cerebral cavernous malformations 2 protein isoform X1. (476 aa)    
Predicted Functional Partners:
MAP3K3
Mitogen-activated protein kinase kinase kinase 3 isoform X1.
    
 0.989
PDCD10
Programmed cell death protein 10.
    
 
 0.984
KRIT1
Krev interaction trapped protein 1.
    
 
 0.968
MAP3K2
Mitogen-activated protein kinase kinase kinase 2 isoform X2.
    
 0.814
STK25
Serine/threonine-protein kinase 25 isoform X1.
    
 
 0.785
STK24
Serine/threonine-protein kinase 24 isoform X4.
    
 
 0.765
ENSPCTP00005023807
Mitogen-activated protein kinase kinase 3.
    
 
 0.695
MILR1
Allergin-1 isoform X2.
    
 0.674
RASIP1
Ras-interacting protein 1.
   
 
 0.666
PRSS57
Serine protease 57.
    
 0.654
Your Current Organism:
Physeter catodon
NCBI taxonomy Id: 9755
Other names: P. catodon, Physeter macrocephalus, sperm whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.