STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (530 aa)    
Predicted Functional Partners:
PDPK1
3-phosphoinositide-dependent protein kinase 1 isoform X1.
  
0.854
TRIB3
Tribbles homolog 3-like.
   
0.853
RICTOR
Rapamycin-insensitive companion of mTOR isoform X1.
    
 0.830
APPL1
DCC-interacting protein 13-alpha isoform X1.
    
 
 0.817
APPL2
DCC-interacting protein 13-beta isoform X1.
    
 
 0.813
TSC2
Tuberin isoform X4.
    
 0.786
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.778
FOXO1
Forkhead box protein O1.
    
 0.777
PIK3R1
Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.
   
 0.763
PHLPP2
PH domain leucine-rich repeat-containing protein phosphatase 2.
    
 0.748
Your Current Organism:
Physeter catodon
NCBI taxonomy Id: 9755
Other names: P. catodon, Physeter macrocephalus, sperm whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.