STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL17Finterleukin-17F isoform X1. (165 aa)    
Predicted Functional Partners:
IL17RA
Interleukin-17 receptor A.
    
 0.996
IL17RC
Interleukin-17 receptor C isoform X1.
    
 0.995
IL17A
interleukin-17A isoform X2.
  
0.991
IL22
Interleukin-22.
   
  
 0.770
IL17RD
Interleukin-17 receptor D.
    
 0.770
IL21
Interleukin; Belongs to the IL-15/IL-21 family.
   
  
 0.721
CCR6
C-C chemokine receptor type 6; Belongs to the G-protein coupled receptor 1 family.
      
 0.700
IL23R
Interleukin-23 receptor isoform X1.
   
  
 0.681
STAT3
Signal transducer and activator of transcription.
   
 0.677
IFNG
Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
   
  
 0.661
Your Current Organism:
Physeter catodon
NCBI taxonomy Id: 9755
Other names: P. catodon, Physeter macrocephalus, sperm whale
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