STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNFRSF25Tumor necrosis factor receptor superfamily member 25. (415 aa)    
Predicted Functional Partners:
TNFSF15
Tumor necrosis factor ligand superfamily member 15.
    
 0.966
TNF
Tumor necrosis factor; Belongs to the tumor necrosis factor family.
    
 0.809
TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1.
    
 0.795
RIPK1
Receptor-interacting serine/threonine-protein kinase 1 isoform X1.
   
 0.721
RNF31
E3 ubiquitin-protein ligase RNF31 isoform X3.
    
 0.680
LTA
Lymphotoxin-alpha; Belongs to the tumor necrosis factor family.
    
 0.676
TNFAIP3
Tumor necrosis factor alpha-induced protein 3 isoform X1.
    
 0.671
CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD isoform X1; Belongs to the peptidase C19 family.
    
 0.664
SHARPIN
Sharpin isoform X2.
    
 0.645
RBCK1
ranBP-type and C3HC4-type zinc finger-containing protein 1 isoform X2.
    
 0.644
Your Current Organism:
Physeter catodon
NCBI taxonomy Id: 9755
Other names: P. catodon, Physeter macrocephalus, sperm whale
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.