TCF4 protein (Physeter catodon) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

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Textmining

[Homology]

Score

TCF4

Transcription factor 4 isoform X1. (677 aa)

Predicted Functional Partners:

CTNNB1

0.973

TAL1

0.895

MYOD1

0.820

MYF5

0.771

ASCL2

0.755

ASCL1

0.755

MYOG

0.750

LMO2

0.746

ASCL4

0.713

RUNX1T1

0.698

Your Current Organism:

Physeter catodon

NCBI taxonomy Id: 9755
Other names: P. catodon, Physeter macrocephalus, sperm whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASCL1	TCF4	ENSPCTP00005023500	ENSPCTP00005007726	Achaete-scute homolog 1.	Transcription factor 4 isoform X1.	0.755
ASCL2	CTNNB1	ENSPCTP00005011314	ENSPCTP00005026275	Achaete-scute homolog 2.	Catenin beta-1.	0.460
ASCL2	TCF4	ENSPCTP00005011314	ENSPCTP00005007726	Achaete-scute homolog 2.	Transcription factor 4 isoform X1.	0.755
ASCL4	TCF4	ENSPCTP00005007694	ENSPCTP00005007726	Achaete-scute homolog 4.	Transcription factor 4 isoform X1.	0.713
CTNNB1	ASCL2	ENSPCTP00005026275	ENSPCTP00005011314	Catenin beta-1.	Achaete-scute homolog 2.	0.460
CTNNB1	MYOD1	ENSPCTP00005026275	ENSPCTP00005009181	Catenin beta-1.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.440
CTNNB1	TCF4	ENSPCTP00005026275	ENSPCTP00005007726	Catenin beta-1.	Transcription factor 4 isoform X1.	0.973
LMO2	TAL1	ENSPCTP00005012895	ENSPCTP00005020718	Rhombotin-2.	T-cell acute lymphocytic leukemia protein 1.	0.994
LMO2	TCF4	ENSPCTP00005012895	ENSPCTP00005007726	Rhombotin-2.	Transcription factor 4 isoform X1.	0.746
MYF5	MYOD1	ENSPCTP00005022940	ENSPCTP00005009181	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.439
MYF5	MYOG	ENSPCTP00005022940	ENSPCTP00005027410	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Myogenin.	0.680
MYF5	TCF4	ENSPCTP00005022940	ENSPCTP00005007726	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Transcription factor 4 isoform X1.	0.771
MYOD1	CTNNB1	ENSPCTP00005009181	ENSPCTP00005026275	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Catenin beta-1.	0.440
MYOD1	MYF5	ENSPCTP00005009181	ENSPCTP00005022940	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.439
MYOD1	MYOG	ENSPCTP00005009181	ENSPCTP00005027410	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Myogenin.	0.759
MYOD1	TCF4	ENSPCTP00005009181	ENSPCTP00005007726	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Transcription factor 4 isoform X1.	0.820
MYOG	MYF5	ENSPCTP00005027410	ENSPCTP00005022940	Myogenin.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.680
MYOG	MYOD1	ENSPCTP00005027410	ENSPCTP00005009181	Myogenin.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.759
MYOG	TAL1	ENSPCTP00005027410	ENSPCTP00005020718	Myogenin.	T-cell acute lymphocytic leukemia protein 1.	0.416
MYOG	TCF4	ENSPCTP00005027410	ENSPCTP00005007726	Myogenin.	Transcription factor 4 isoform X1.	0.750